Day 1 — Ancient RomeMorning: Colosseum (pre-book tickets — queues without are brutal)Midday: Roman Forum and Palatine HillAfternoon: Circus Maximus and Aventine HillEvening: Trastevere neighborhood for dinner — cacio e pepe and supplìDay 2 — Vatican CityDawn: Vatican Museums and Sistine Chapel (book the first morning slot)Midday: St. Peter's Basilica and climb the dome for panoramic viewsAfternoon: Castel Sant'Angelo walkway along the TiberEvening: Campo de' Fiori for aperitivo and nightlifeDay 3 — Baroque RomeMorning: Pantheon (free, go early) and surrounding piazzasMidday: Piazza Navona and its Baroque fountainsAfternoon: Trevi Fountain, Spanish Steps, Villa BorgheseEvening: Prati neighborhood near the Vatican for excellent trattoriasDay 4 — Hidden RomeMorning: Aventine Keyhole view of St. Peter's through the Knights of Malta gardenMidday: Testaccio neighborhood market — Rome's most authentic food quarterAfternoon: Appian Way by bike — ancient road lined with catacombs and ruinsEvening: Farewell dinner in the Jewish Ghetto: artichokes alla giudia